Estrogen Receptor alpha Antibody

NSJ Bioreagents
Product Code: NSJ-V7746
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V7746-0.1ML0.1 ml£264.00
Quantity:
NSJ-V7746-0.5ML0.5 ml£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 1D5
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Estrogen Receptor alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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IHC staining of FFPE human endometrial carcinoma with Estrogen Receptor alpha antibody (clone 1D5). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

IHC staining of FFPE human endometrial carcinoma with Estrogen Receptor alpha antibody (clone 1D5). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

Further Information

Application Details :
Immunohistochemistry (FFPE): 1:100-1:200
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
Format :
Culture supernatant
Formulation :
Culture supernatant with 0.05% sodium azide
Immunogen:
Recombinant human protein was used as the immunogen for this Estrogen Receptor alpha antibody.
Limitation:
This Estrogen Receptor alpha antibody is available for research use only.
Localization:
Nuclear
Purity:
Unpurified high titer supernatant
Species Reactivity :
Human
Uniprot #:
P03372