Estrogen Receptor alpha Antibody

NSJ Bioreagents
Product Code: NSJ-F40335
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F40335-0.08ML0.08 ml£260.00
Quantity:
NSJ-F40335-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 415CT16.3.2.1
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the Estrogen Receptor alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Estrogen Receptor alpha antibody western blot analysis in MCF-7 lysate. Predicted molecular weight: 65-70 kDa.

Estrogen Receptor alpha antibody western blot analysis in MCF-7 lysate. Predicted molecular weight: 65-70 kDa.

Further Information

Application Details :
Western blot: 1:100-1:250
Application Note:
Titration of the Estrogen Receptor alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 246-273 from the human protein was used as the immunogen for this Estrogen Receptor alpha antibody.
Limitation:
This Estrogen Receptor alpha antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Bovine, Mouse, Pig, Rat
Uniprot #:
P03372