Aurora B Antibody / AURKB
| Code | Size | Price |
|---|
| NSJ-V3927-20UG | 20 ug | £264.00 |
Quantity:
| NSJ-V3927-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: ARRK2-1
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the AURKB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Documents
Further Information
Application Details :
IHC (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the AURKB antibody should be determined by the researcher.
Description:
Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
Amino acids 89-251 were used as the immunogen for this AURKB antibody.
Limitation:
This AURKB antibody is available for research use only.
Localization:
Nuclear, cytoplasmic
Purity:
Protein G affinity
Species Reactivity :
Human
Uniprot #:
Q96GD4