CD19 Antibody / B-lymphocyte marker
Code | Size | Price |
---|
NSJ-V7076-20UG | 20 ug | £264.00 |
Quantity:
NSJ-V7076-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: CDLA19-1
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
Storage:
CD19 antibody with azide can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20oC or colder.
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Further Information
Application Details :
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,,
Application Note:
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD19 antibody to be titered up or down for optimal performance.
Description:
CD19 is expressed on follicular dendritic cells and B cells. It is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. [Wiki]
Format :
Purified
Formulation :
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
Human recombinant full length protein was used as immunogen for this CD19 antibody.
Limitation:
This CD19 antibody is available for research use only.
Localization:
Cell surface, cytoplasmic
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P15391