Chromogranin A Antibody

NSJ Bioreagents
Product Code: NSJ-V3825
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V3825-20UG20 ug£264.00
Quantity:
NSJ-V3825-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG, kappa
Antibody Clonality: Recombinant Antibody
Antibody Clone: CHGA/1815R
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the recombinant Chromogranin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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IHC analysis of FFPE human pancreas stained with recombinant Chromogranin A antibody (clone CHGA/1815R). Required HIER: steam sections in pH6 citrate buffer for 10-20 min.~
2 / 2
SDS-PAGE analysis of purified, BSA-free recombinant Chromogranin

IHC analysis of FFPE human pancreas stained with recombinant Chromogranin A antibody (clone CHGA/1815R). Required HIER: steam sections in pH6 citrate buffer for 10-20 min.~
SDS-PAGE analysis of purified, BSA-free recombinant Chromogranin

Further Information

Application Details :
Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT
Application Note:
Optimal dilution of the recombinant Chromogranin A antibody should be determined by the researcher.
Description:
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
Recombinant human protein was used as the immunogen for the recombinant Chromogranin A antibody.
Limitation:
This recombinant Chromogranin A antibody is available for research use only.
Localization:
Cytoplasmic
Microarray Validated?:
Yes
Purity:
Protein A affinity chromatography
Species Reactivity :
Human
Uniprot #:
P10645