SULT1E1 Antibody / Estrogen Sulfotransferase

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NSJ Bioreagents
Product Code: NSJ-V7520
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V7520-20UG20 ug£264.00
Quantity:
NSJ-V7520-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: CPTC-SULT1E1-1
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store the SULT1E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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Western blot testing of human liver lysate with SULT1E1 antibody (clone CPTC-SULT1E1-1). Expected molecular weight ~33-35 kDa.~
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IHC staining of FFPE human small intestine with SULT1E1 antibody. Required HIER: boil tissue sections in pH6,
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Western blot testing of human liver lysate with SULT1E1 antibody (clone CPTC-SULT1E1-1). Expected molecular weight ~33-35 kDa.~
IHC staining of FFPE human small intestine with SULT1E1 antibody. Required HIER: boil tissue sections in pH6,

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT,Western blot: 1-2ug/ml
Application Note:
Optimal dilution of the SULT1E1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Description:
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
Recombinant human protein was used as the immunogen for the SULT1E1 antibody.
Limitation:
This SULT1E1 antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P49888