Melanoma Marker Antibody Cocktail (MART-1 & Tyrosinase & gp100)
Code | Size | Price |
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NSJ-V8328-20UG | 20 ug | £264.00 |
Quantity:
NSJ-V8328-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2b, kappa + Mouse IgG1, kappa + Mouse IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: DT101+ BC199 + T311 + HMB45
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Melanoma Marker antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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Further Information
Application Details :
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Format :
Purified
Formulation :
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
Recombinant hMART-1 protein (DT101 & BC199), extract of pigmented melanoma metastases from lymph nodes (HMB45) and recombinant tyrosinase protein (T311) were used as the immunogen for this Melanoma Marker antibody cocktail.
Limitation:
This Melanoma Marker antibody cocktail is available for research use only.
Purity:
Protein G affinity chromatography
Species Reactivity :
Human