ENAH Antibody / Mena

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NSJ Bioreagents
Product Code: NSJ-V7474
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V7474-20UG20 ug£264.00
Quantity:
NSJ-V7474-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2c, kappa
Antibody Clonality: Monoclonal
Antibody Clone: ENAH/1988
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Store the ENAH antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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Western blot testing of human HeLa and MCF-7 lysate with ENAH antibody. Predicted molecular weight ~66 kDa but can be observed at ~90 kDa.~
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using EN
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Western blot testing of human HeLa and MCF-7 lysate with ENAH antibody. Predicted molecular weight ~66 kDa but can be observed at ~90 kDa.~
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using EN

Documents

Further Information

Application Details :
ELISA (order BSA/sodium azide-free format for coating),Western blot: 1-2ug/ml
Application Note:
The stated application concentrations are suggested starting points. Titration of the ENAH antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
A portion of amino acids 485-589 from the human protein was used as the immunogen for the ENAH antibody.
Limitation:
This ENAH antibody is available for research use only.
Microarray Validated?:
Yes
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
Q8N8S7