Glycoprotein 2 Antibody / GP2 / ZAP75

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NSJ Bioreagents
Product Code: NSJ-V7816
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V7816-20UG20 ug£264.00
Quantity:
NSJ-V7816-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2c, kappa
Antibody Clonality: Monoclonal
Antibody Clone: GP2/3416
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store the Glycoprotein 2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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IHC testing of FFPE human pancreas with Glycoprotein 2 antibody (clone GP2/3416). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
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IHC testing of FFPE human pancreas with Glycoprotein 2 antibody (clone GP2/3416). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
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Western blot testing of human pancreas lysate with Glycoprotein 2 antibody (clone GP2/3416).
4 / 4
SDS-PAGE analysis of purified, BSA-free Glycoprotein 2 antibody (clone GP2/3416) as confirmation of integrity and purity.
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IHC testing of FFPE human pancreas with Glycoprotein 2 antibody (clone GP2/3416). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
IHC testing of FFPE human pancreas with Glycoprotein 2 antibody (clone GP2/3416). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
Western blot testing of human pancreas lysate with Glycoprotein 2 antibody (clone GP2/3416).
SDS-PAGE analysis of purified, BSA-free Glycoprotein 2 antibody (clone GP2/3416) as confirmation of integrity and purity.

Documents

Further Information

Application Details :
Western blot: 1-2ug/ml,Immunohistochemistry: 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Format :
Purified
Formulation :
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant human partial protein (amino acids 35-179) was used as the immunogen for this Glycoprotein 2 antibody.
Limitation:
This Glycoprotein 2 antibody is available for research use only.
Localization:
Cytoplasmic, membranous, secreted
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P55259