IKKb Antibody
| Code | Size | Price |
|---|
| NSJ-N1030-25UG | 25 ug | £254.00 |
Quantity:
| NSJ-N1030-100UG | 100 ug | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: IKB355
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Aliquot the IKKb antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 2-4ug/ml
Application Note:
Provided assay concentrations are suggestions only, IKKb antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
NF-kB is sequestered in the cytoplasm by IkBa, unable to translocate to the nucleus. IkB is part of the canonical pathway for NF-kB activation. IKKb is part of the IkB kinase complex, along with a second catalytic subunit, IKKa, and a regulatory subunit, IKKg. Along with IKKa, IKKb phosphorylates IkBa leading to its degradation and release of inhibition of NF-kB. The RELA subunit of active NF-kB is then free to enter the nucleus and initiate a number of signaling cascades.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
3551
Immunogen:
A recombinant protein fragment of IKKb was used as the immunogen for this antibody.
Limitation:
This IKKb antibody is available for research use only.
Purity:
Protein G purified antibody
Species Reactivity :
Human, Mouse