c-Kit Antibody / CD117
| Code | Size | Price |
|---|
| NSJ-V2648-20UG | 20 ug | £264.00 |
Quantity:
| NSJ-V2648-100UG | 100 ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: KIT/982
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the c-Kit antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Documents
Further Information
Application Details :
Western blot: 0.5-1ug/ml for 2 hours at RT
Application Note:
Optimal dilution of the c-Kit antibody should be determined by the researcher.
Description:
This mAb recognizes a protein of 145kDa, identified as CD117/p145kit/c-Kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117/c-Kit has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117/c-Kit is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
A recombinant human fragment around amino acids 100-300 was used as the immunogen for the c-Kit antibody.
Limitation:
This c-Kit antibody is available for research use only.
Localization:
Cell surface and cytoplasmic
Microarray Validated?:
Yes
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P10721