Cytokeratin 5 Antibody / KRT5
| Code | Size | Price |
|---|
| NSJ-V7911-0.1ML | 0.1 ml | £264.00 |
Quantity:
| NSJ-V7911-0.5ML | 0.5 ml | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: KRT5/2080
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Cytokeratin 5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Documents
Further Information
Application Details :
Immunohistochemistry (FFPE): 1:50-1:100
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This MAb recognizes a protein of 58kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express.Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.
Format :
Culture supernatant
Formulation :
Culture supernatant with 0.05% sodium azide
Immunogen:
A recombinant human partial protein (amino acids 318-491) was used as the immunogen for this Cytokeratin 5 antibody.
Limitation:
This Cytokeratin 5 antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Unpurified high titer supernatant
Species Reactivity :
Human
Uniprot #:
P13647