MCM7 Antibody

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NSJ Bioreagents
Product Code: NSJ-V3503
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V3503-20UG20 ug£264.00
Quantity:
NSJ-V3503-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: MCM7/1468
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store the MCM7 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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Protein array validation of the MCM7 antibody: Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using MCM7 antibody (clone MCM7/1468). These results demonstrate the foremost specificity of the MCM7/1468 mAb.<P><P>Z- and S- score: The Z-score represents the strength of
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Protein array validation of the MCM7 antibody: Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using MCM7 antibody (clone MCM7/1468). These results demonstrate the foremost specificity of the MCM7/1468 mAb.<P><P>Z- and S- score: The Z-score represents the strength of

Documents

Further Information

Application Details :
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Titering of the MCM7 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Description:
MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
A human partial recombinant protein corresponding to amino acids 195-319 was used as the immunogen for the MCM7 antibody.
Limitation:
This MCM7 antibody is available for research use only.
Localization:
Nuclear
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P33993