NKIRAS1 Antibody
| Code | Size | Price |
|---|
| NSJ-N1127-25UG | 25 ug | £254.00 |
Quantity:
| NSJ-N1127-100UG | 100 ug | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: NRAS285
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Storage:
Aliquot the NKIRAS1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 5-10ug/ml
Application Note:
Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.
NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
28512
Immunogen:
A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
Limitation:
This NKIRAS1 antibody is available for research use only.
Purity:
Protein G purified antibody
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q9NYS0