PAX7 Antibody

Immunofluorescence: 0.5-1ug/ml,Flow cytometry: 0.5-1ug/million cells,Western blot: 0.5-1ug/ml

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

The PAX gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the PAX family of proteins have been linked to disease and cancer in humans. PAX7 is a protein specifically expressed in cultured satellite cell- derived myoblasts. In situ hybridization reveals that PAX7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding PAX7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

5081

Recombinant human PAX7 protein corresponding to amino acids 301-505 was used as the immunogen for this antibody.

This PAX7 antibody is available for research use only.

Nuclear

Protein G affinity chromatography

Human, Mouse, Rat