Progesterone Receptor Antibody

Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

The optimal dilution of the Progesterone Receptor antibody for each application should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than estrogen receptor (ER) alone. This MAb is excellent for immunohistochemical staining of formalin-fixed tissues.

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

A portion of amino acids 483-571 from the human protein was used as the immunogen for this Progesterone Receptor antibody.

This Progesterone Receptor antibody is available for research use only.

Nuclear, cytoplasmic

Yes

Protein G affinity chromatography

Human

P06401