Podocalyxin Antibody / PODXL

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NSJ Bioreagents
Product Code: NSJ-V3917
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V3917-20UG20 ug£264.00
Quantity:
NSJ-V3917-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: PODXL/2185
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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IHC testing of FFPE human endometrium with Podocalyxin antibody (clone PODXL/2185). HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.~
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IHC testing of FFPE human placenta with Podo
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IHC testing of FFPE human endometrium with Podocalyxin antibody (clone PODXL/2185). HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.~
IHC testing of FFPE human placenta with Podo

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the Podocalyxin antibody should be determined by the researcher.
Description:
Podocalyxin/PODXL is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
A portion of amino acids 310-447 from the human protein was used as the immunogen for the Podocalyxin antibody.
Limitation:
This Podocalyxin antibody is available for research use only.
Localization:
Cell surface and cytoplasmic
Microarray Validated?:
Yes
Purity:
Protein G affinity
Species Reactivity :
Human
Uniprot #:
O00592