Progesterone Receptor Antibody

NSJ Bioreagents
Product Code: NSJ-V2225
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V2225-20UG20 ug£264.00
Quantity:
NSJ-V2225-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: PR500
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the Progesterone receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

1 / 2
IHC testing of human breast carcinoma stained with progesterone receptor antibody (PR500).~
2 / 2
SDS-PAGE Analysis of Purified, BSA-Free Progesterone Receptor Antibody (clone PR500). Confirmation of Integrity and Purity of the Antibody.

IHC testing of human breast carcinoma stained with progesterone receptor antibody (PR500).~
SDS-PAGE Analysis of Purified, BSA-Free Progesterone Receptor Antibody (clone PR500). Confirmation of Integrity and Purity of the Antibody.

Further Information

Application Details :
Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.

Description:
This antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of progesterone receptor has been suggested to reflect a intact estrogen regulatory machinery and therefore predict better clinical response to endocrine therapy than ER alone.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Gene ID #:
5241 (Human)
Immunogen:
Recombinant human Progesterone Receptor protein was used as the immunogen for this antibody.
Limitation:
This Progesterone receptor antibody is available for research use only.
Localization:
Nuclear, cytoplasmic
Purity:
Protein G affinity chromatography
Species Reactivity :
Human