S100A8 Antibody
| Code | Size | Price |
|---|
| NSJ-N1151-25UG | 25 ug | £254.00 |
Quantity:
| NSJ-N1151-100UG | 100 ug | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SA6279
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the S100A8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 2-4ug/ml
Application Note:
Provided assay concentrations are suggestions only, S100A8 antibody titration may be required for optimal results.
Buffer:
1X PBS, pH 7.4
Description:
The S100 family of proteins are found in vertebrates and are characterized by two calcium-binding sites that have a helix-loop-helix conformation. The family of 24 is divided into three subgroups based on function: those with intracellular, intracellular plus extracellular, and extracellular regulatory effects. The calcium-binding protein S100A8, also called MRP8 or Myeloid-related protein 8, and Calgranulin A, forms a heterodimer with S100A9, called Calprotectin. The heterodimer is expressed by granulocytes, monocytes, and early differentiation states of macrophages, and is known to be an important pro-inflammatory mediator in acute and chronic inflammation. S100A8 and 9 are DAMPs, or Damage-associated molecular pattern molecules, and are able to activate receptors of the innate immune system, one being TLR4.
Format :
Purified
Formulation :
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Gene ID #:
6279
Immunogen:
A recombinant protein fragment from the N-terminal region of human S100A8 was used as the immunogen for this antibody.
Limitation:
This S100A8 antibody is available for research use only.
Purity:
Protein G affinity chromatography
Species Reactivity :
Human