SDHB Antibody

NSJ Bioreagents
Product Code: NSJ-V8073
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V8073-20UG20 ug£264.00
Quantity:
NSJ-V8073-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SDHB/2382
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the SDHB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SDHB antibody (clone SDHB/2382). These results demonstrate the foremost specificity of the SDHB/2382 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a flu

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using SDHB antibody (clone SDHB/2382). These results demonstrate the foremost specificity of the SDHB/2382 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a flu

Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Succinate dehydrogenase (SDH) is Complex II in the mitochondria, vital for mitochondrial electron transport, as well as Krebs cycle function.Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation.Antibody to SDHB is helpful in the identification of phaeochromocytomas, paragangliomas and GIST.
Format :
Purified
Formulation :
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant human partial protein (amino acids 165-273) were used as the immunogen for this SDHB antibody.
Limitation:
This SDHB antibody is available for research use only.
Microarray Validated?:
Yes
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P21912