CD6 Antibody

NSJ Bioreagents
Product Code: NSJ-V9104
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V9104-20UG20 ug£264.00
Quantity:
NSJ-V9104-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SPM547
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store the anti-CD6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

1 / 2
IHC: Formalin-fixed, paraffin-embedded human tonsil stained with anti-CD6 antibody (clone SPM547).~
2 / 2
Immunofluorescent staining of human MOLT4 cells with CD6 antibody (green, clone SPM547) and Reddot nuclear stain (red).

IHC: Formalin-fixed, paraffin-embedded human tonsil stained with anti-CD6 antibody (clone SPM547).~
Immunofluorescent staining of human MOLT4 cells with CD6 antibody (green, clone SPM547) and Reddot nuclear stain (red).

Further Information

Application Details :
Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular 'scavenger receptor cysteine-rich' (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
Human recombinant protein was used as the immunogen for this anti-CD6 antibody.
Limitation:
This anti-CD6 antibody is available for research use only.
Localization:
Cell surface and Cytoplasmic
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P30203