PGP9.5 / UchL1 Antibody

NSJ Bioreagents
Product Code: NSJ-V9097
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V9097-20UG20 ug£264.00
Quantity:
NSJ-V9097-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SPM575
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the anti-UchL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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Western blot testing of human brain lysate with anti-UchL1 antibody (clone SPM575). Predicted molecular weight ~25 kDa.~
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SDS-PAGE analysis of purified, BSA-free anti-UchL1 antibody (clone SPM575) as confirmation of integrity and purity.

Western blot testing of human brain lysate with anti-UchL1 antibody (clone SPM575). Predicted molecular weight ~25 kDa.~
SDS-PAGE analysis of purified, BSA-free anti-UchL1 antibody (clone SPM575) as confirmation of integrity and purity.

Further Information

Application Details :
Western blot: 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, UchL1 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for UchL1 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in the gene is believed to cause a form of Parkinson's disease.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
Native UchL1/PGP9.5 protein isolated from human brain was used as the immunogen for this anti-UchL1 antibody.
Limitation:
This anti-UchL1 antibody is available for research use only.
Localization:
Cytoplasmic. Endoplasmic Reticulum membrane
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P09936