CEA Antibody / Carcinoembryonic Antigen

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NSJ Bioreagents
Product Code: NSJ-V9008
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V9008-20UG20 ug£264.00
Quantity:
NSJ-V9008-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SPM584
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store the CEA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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IHC: Formalin-fixed, paraffin-embedded human colon carcinoma stained with CEA antibody (SPM584).~
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Western blot of human human stomach lysate using CEA antibody (SPM584). Expected molecular weight: 80~200 kDa depending on glycosylation le
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IHC: Formalin-fixed, paraffin-embedded human colon carcinoma stained with CEA antibody (SPM584).~
Western blot of human human stomach lysate using CEA antibody (SPM584). Expected molecular weight: 80~200 kDa depending on glycosylation le

Documents

Further Information

Application Details :
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This mAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
Human colon carcinoma extract was used as the immunogen for this CEA antibody.
Limitation:
This CEA antibody is available for research use only.
Localization:
Cytoplasmic and luminal surface
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P06731