MRP1 Antibody / ABCC1

NSJ Bioreagents
Product Code: NSJ-F49725
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F49725-0.08ML0.08 ml£260.00
Quantity:
NSJ-F49725-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Fluorescence-activated cell sorting (FACS)
  • Western Blot (WB)
Storage:
Aliquot the MRP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of MRP1 antibody and human Ramos lysate. Predicted molecular weight of multiple isoforms: 159~172 kDa.~
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Flow cytometric analysis of human NCI-H292 cells using MRP1 antibody (bottom histogram) compared to a <a href

Western blot analysis of MRP1 antibody and human Ramos lysate. Predicted molecular weight of multiple isoforms: 159~172 kDa.~
Flow cytometric analysis of human NCI-H292 cells using MRP1 antibody (bottom histogram) compared to a <a href

Further Information

Application Details :
Western blot: 1:1000,Flow Cytometry: 1:10-1:50
Description:
ABCC1, also called Multidrug resistance-associated protein 1 (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC gene are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1247-1275 from the human protein was used as the immunogen for this MRP1 antibody.
Limitation:
This MRP1 antibody is available for research use only.
Localization:
Cell surface, cytoplasmic
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Mouse, Bovine, Primate
Uniprot #:
P33527