APC11 Antibody / ANAPC11

NSJ Bioreagents
Product Code: NSJ-F53960
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F53960-0.05ML0.05 ml£260.00
Quantity:
NSJ-F53960-0.2ML0.2 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the APC11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of human 1) HeLa, 2) PC-3, 3) T47D and 4) U-2OS cell lysate with APC11 antibody at 1:2000. Predicted molecular weight: ~10 kDa (Q9NYG5-1) or ~20 kDa (Q9NYG5-2).

Western blot testing of human 1) HeLa, 2) PC-3, 3) T47D and 4) U-2OS cell lysate with APC11 antibody at 1:2000. Predicted molecular weight: ~10 kDa (Q9NYG5-1) or ~20 kDa (Q9NYG5-2).

Further Information

Application Details :
Western blot: 1:1000-2000
Description:
Anaphase-promoting complex subunit 11, together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Gene ID #:
51529
Immunogen:
A portion of amino acids 56-94 from the human protein was used as the immunogen for the APC11 antibody.
Limitation:
This APC11 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Species Reactivity (Predicted):
Bovine, Mouse
Uniprot #:
Q9NYG5