BACE2 Antibody
| Code | Size | Price |
|---|
| NSJ-F49441-0.08ML | 0.08 ml | £260.00 |
Quantity:
| NSJ-F49441-0.4ML | 0.4 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Fluorescence-activated cell sorting (FACS)
- Western Blot (WB)
Storage:
Aliquot the BACE2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 1:1000,Flow Cytometry: 1:10-1:50
Application Note:
Titration of the BACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 336-365 from the human protein was used as the immunogen for this BACE2 antibody.
Limitation:
This BACE2 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
Q9Y5Z0