BAX Antibody

NSJ Bioreagents
Product Code: NSJ-F52764
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F52764-0.08ML0.08 ml£260.00
Quantity:
NSJ-F52764-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the BAX antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of lysate from 1) HeLa, 2) 293, 3) HT-1080, 4) Raji, 5) SH-SY5Y and 6) THP-1 cell line using BAX antibody at 1:1000.

Western blot analysis of lysate from 1) HeLa, 2) 293, 3) HT-1080, 4) Raji, 5) SH-SY5Y and 6) THP-1 cell line using BAX antibody at 1:1000.

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the BAX antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This BAX antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 47-78 amino acids from the N-terminal region of human BAX.
Limitation:
This BAX antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q07812