GPNMB Antibody

NSJ Bioreagents
Product Code: NSJ-F45454
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F45454-0.08ML0.08 ml£260.00
Quantity:
NSJ-F45454-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the GPNMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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GPNMB antibody western blot analysis in CEM lysate.

GPNMB antibody western blot analysis in CEM lysate.

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the GPNMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 541-569 from the human protein was used as the immunogen for this GPNMB antibody.
Limitation:
This GPNMB antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q14956