Integrin alpha 3 Antibody

NSJ Bioreagents
Product Code: NSJ-F53345
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F53345-0.08ML0.08 ml£260.00
Quantity:
NSJ-F53345-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the Integrin alpha 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of Integrin alpha 3 antibody at 1:4000 dilution and 1) A431 lysate, 2) HeLa lysate, and 3) PC3 lysate at 1:2000. Expected molecular weight: 119-150 kDa depending on glycosylation level.

Western blot testing of Integrin alpha 3 antibody at 1:4000 dilution and 1) A431 lysate, 2) HeLa lysate, and 3) PC3 lysate at 1:2000. Expected molecular weight: 119-150 kDa depending on glycosylation level.

Further Information

Application Details :
Western blot: 1:2000-4000
Application Note:
Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This Integrin alpha 3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human ITGA3.
Limitation:
This Integrin alpha 3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P26006