KLF4 Antibody

NSJ Bioreagents
Product Code: NSJ-F48146
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F48146-0.08ML0.08 ml£260.00
Quantity:
NSJ-F48146-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the KLF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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KLF4 antibody western blot analysis in (1) HeLa,(2) MCF-7 and (3) SW480 lysate. Predicted molecular weight: 50-60 kDa + ~75 kDa

KLF4 antibody western blot analysis in (1) HeLa,(2) MCF-7 and (3) SW480 lysate. Predicted molecular weight: 50-60 kDa + ~75 kDa

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 20-53 from the human protein was used as the immunogen for this KLF4 antibody.
Limitation:
This KLF4 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
O43474