NLRP6 Antibody

NSJ Bioreagents
Product Code: NSJ-F43035
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F43035-0.08ML0.08 ml£260.00
Quantity:
NSJ-F43035-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the NLRP6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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NLRP6antibody western blot analysis in human placenta tissue lysate.
2 / 3
Western blot testing of human 1) Jurkat, 2) U266B1, 3) RPMI 8226, 4) HT-29 and 5) SW480 lysate with NLRP9 antibody. Predicted molecular weight ~99 kDa.
3 / 3
Western blot testing of human 1) placenta, 2) HL-60, 3) Jurkat and 4) U266B1 lysate with NLRP9 antibody. Predicted molecular weight ~99 kDa.

NLRP6antibody western blot analysis in human placenta tissue lysate.
Western blot testing of human 1) Jurkat, 2) U266B1, 3) RPMI 8226, 4) HT-29 and 5) SW480 lysate with NLRP9 antibody. Predicted molecular weight ~99 kDa.
Western blot testing of human 1) placenta, 2) HL-60, 3) Jurkat and 4) U266B1 lysate with NLRP9 antibody. Predicted molecular weight ~99 kDa.

Further Information

Application Details :
Western blot: 1:1000-1:4000
Application Note:
Titration of the NLRP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1, also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 168-197 from the human protein was used as the immunogen for this NLRP6 antibody.
Limitation:
This NLRP6 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P59044