p70 S6 Kinase Antibody

NSJ Bioreagents
Product Code: NSJ-F48467
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F48467-0.08ML0.08 ml£260.00
Quantity:
NSJ-F48467-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the p70 S6 Kinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 1
Western blot analysis of p70 S6 Kinase antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RPS6KB1 gene (2). Predicted molecular weight: 60-70 kDa

Western blot analysis of p70 S6 Kinase antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RPS6KB1 gene (2). Predicted molecular weight: 60-70 kDa

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the p70 S6 Kinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 405-434 from the human protein was used as the immunogen for this p70 S6 Kinase antibody.
Limitation:
This p70 S6 Kinase antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Species Reactivity (Predicted):
Bovine, Mouse, Rabbit, Rat
Uniprot #:
P23443