Phospho-CDC25A Antibody (pS293)

NSJ Bioreagents
Product Code: NSJ-F48377
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F48377-0.08ML0.08 ml£260.00
Quantity:
NSJ-F48377-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the phospho-CDC25A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of phospho-CDC25A antibody and cells transfected with wild type or mutant S293A of CDC25A. Data courtesy of Dr. Tiebang Kang of Washington University, St. Louis, MO.

Western blot testing of phospho-CDC25A antibody and cells transfected with wild type or mutant S293A of CDC25A. Data courtesy of Dr. Tiebang Kang of Washington University, St. Louis, MO.

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the phospho-CDC25A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This phospho-CDC25A antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS293 of human CDC25A.
Limitation:
This phospho-CDC25A antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P30304