SUMO-2 Antibody

NSJ Bioreagents
Product Code: NSJ-F42016
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F42016-0.08ML0.08 ml£260.00
Quantity:
NSJ-F42016-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the SUMO-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of SUMO-2 antibody and 293 cell lysate. Observed molecular weight: 12-15 kDa.~
2 / 2
Western blot analysis of SUMO-2 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2)

Western blot analysis of SUMO-2 antibody and 293 cell lysate. Observed molecular weight: 12-15 kDa.~
Western blot analysis of SUMO-2 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2)

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the SUMO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
SUMO2 and SUMO3 are members of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This SUMO-2 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide from the human protein.
Limitation:
This SUMO-2 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P61956