Transglutaminase 2 Antibody

NSJ Bioreagents
Product Code: NSJ-F50805
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F50805-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50805-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot the TG2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of TG2 antibody and 293 cell lysate (2 ug/lane) either nontransfected or transiently transfected with the TGM2 gene.

Western blot analysis of TG2 antibody and 293 cell lysate (2 ug/lane) either nontransfected or transiently transfected with the TGM2 gene.

Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the TG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 413-442 from the human protein was used as the immunogen for this TG2 antibody.
Limitation:
This TG2 antibody is available for research use only.
Purity:
SAS immunoprecipitation purified
Species Reactivity :
Human
Uniprot #:
P21980