NSJ Bioreagents

Estrogen Receptor Antibody (isoform 4)

Product Code:
 
NSJ-F47480
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
 
Aliquot the Estrogen Receptor antibody (isoform 4) and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
1 / 2
Fluorescent confocal image of MCF-7 cell stained with Estrogen Receptor antibody at 1:25. ER (isoform 4) immunoreactivity is localized to the cytoplasm.~
2 / 2
Estrogen Receptor antibody (isoform 4) western blot analysis in MCF-7 lysate. Pre

Fluorescent confocal image of MCF-7 cell stained with Estrogen Receptor antibody at 1:25. ER (isoform 4) immunoreactivity is localized to the cytoplasm.~
Estrogen Receptor antibody (isoform 4) western blot analysis in MCF-7 lysate. Pre

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CodeSizePrice
NSJ-F47480-0.08ML0.08 ml£260.00
Quantity:
NSJ-F47480-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000,Immunofluorescence: 1:10-1:50
Application Note:
Titration of the Estrogen Receptor antibody (isoform 4) may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 271-300 from the human protein was used as the immunogen for this Estrogen Receptor antibody (isoform 4).
Limitation:
This Estrogen Receptor antibody (isoform 4) is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P03372-4