Caspase-3 Antibody
| Code | Size | Price |
|---|
| NSJ-F50514-0.08ML | 0.08 ml | £260.00 |
Quantity:
| NSJ-F50514-0.4ML | 0.4 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Aliquot the anti-Caspase-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the anti-Caspase-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
CASP3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 60-90 from the human protein was used as the immunogen for this anti-Caspase-3 antibody.
Limitation:
This anti-Caspase-3 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P42574