Claudin 2 Antibody (CLDN2)
| Code | Size | Price |
|---|
| NSJ-F49580-0.08ML | 0.08 ml | £260.00 |
Quantity:
| NSJ-F49580-0.4ML | 0.4 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Aliquot the Claudin 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the Claudin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Claudin-2 is expressed in cation-leaky epithelia such as that of the kidney proximal tubule. Mice that are deficient in the protein have reduced reabsorption of Na+ in the proximal tubule, consistent with a role in paracellular transport. Similar results have been obtained with cultured cells, as overexpression in CLDN2 lacking cells leads to increase of permeability for small cations. Furthermore, CLDN2 has been shown to form paracellular channels for water. [Wiki]
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 135-164 from the human protein was used as the immunogen for this Claudin 2 antibody.
Limitation:
This Claudin 2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Species Reactivity (Predicted):
Mouse, Bovine
Uniprot #:
P57739