NSJ Bioreagents

FGFR3 Antibody

Product Code:
 
NSJ-F50621
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Aliquot the FGFR3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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IHC analysis of FFPE human breast carcinoma tissue stained with the FGFR3 antibody~
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Western blot analysis of FGFR3 antibody and Jurkat cell lysate. Predicted molecular weight: 87-135 kDa depending on glycosylation level.
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IHC analysis of FFPE human breast carcinoma tissue stained with the FGFR3 antibody~
Western blot analysis of FGFR3 antibody and Jurkat cell lysate. Predicted molecular weight: 87-135 kDa depending on glycosylation level.

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CodeSizePrice
NSJ-F50621-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50621-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the FGFR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
FGFR3 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 776-806 from the human protein was used as the immunogen for this FGFR3 antibody.
Limitation:
This FGFR3 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P22607