IGF1R Antibody

NSJ Bioreagents
Product Code: NSJ-F50633
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F50633-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50633-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the IGF1R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC analysis of FFPE human breast carcinoma tissue stained with the IGF1R antibody~
2 / 2
Western blot analysis of IGF1R antibody and SK-BR-3 lysate. Predicted molecular weight: ~200 kDa (pro), 120-130 kDa (alpha), 90-97 kDa (beta).

IHC analysis of FFPE human breast carcinoma tissue stained with the IGF1R antibody~
Western blot analysis of IGF1R antibody and SK-BR-3 lysate. Predicted molecular weight: ~200 kDa (pro), 120-130 kDa (alpha), 90-97 kDa (beta).

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the IGF1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 19-51 from the human protein was used as the immunogen for this IGF1R antibody.
Limitation:
This IGF1R antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Mouse, Rat
Uniprot #:
P08069