MST1 Antibody (Mammalian STE20-like protein kinase 1)

NSJ Bioreagents
Product Code: NSJ-F50888
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F50888-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50888-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the MST1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of MST1 antibody and HL-60 cell lysate. Predicted molecular weight ~ 56 kDa.
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Western blot analysis of STK4 / MST1 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the STK4 gene (2). Predicted molecular weight ~ 56 kDa.
3 / 3
IHC analysis of FFPE human breast carcinoma tissue stained with the MST1 antibody

Western blot analysis of MST1 antibody and HL-60 cell lysate. Predicted molecular weight ~ 56 kDa.
Western blot analysis of STK4 / MST1 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the STK4 gene (2). Predicted molecular weight ~ 56 kDa.
IHC analysis of FFPE human breast carcinoma tissue stained with the MST1 antibody

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the MST1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 385-415 from the human protein was used as the immunogen for this MST1 antibody.
Limitation:
This MST1 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Bovine
Uniprot #:
Q13043