MUC-1 Antibody

NSJ Bioreagents
Product Code: NSJ-F43118
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F43118-0.08ML0.08 ml£260.00
Quantity:
NSJ-F43118-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the MUC-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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MUC-1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue.~
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MUC-1 antibody western blot analysis in NCI-H292 lysate. This Ab will detect the 17-28 kDa isoforms as well as full length MUC1

MUC-1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue.~
MUC-1 antibody western blot analysis in NCI-H292 lysate. This Ab will detect the 17-28 kDa isoforms as well as full length MUC1

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the MUC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1176-1205 from the human protein was used as the immunogen for this MUC-1 antibody.
Limitation:
This MUC-1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P15941