NEDD8 Antibody

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NSJ Bioreagents
Product Code: NSJ-F42040
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F42040-0.08ML0.08 ml£260.00
Quantity:
NSJ-F42040-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the NEDD8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of NEDD8 antibody and HeLa cell lysate~
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IHC analysis of FFPE human hepatocarcinoma stained with the NEDD8 antibody
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Western blot analysis of NEDD8 antibody and HeLa cell lysate~
IHC analysis of FFPE human hepatocarcinoma stained with the NEDD8 antibody

Documents

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the NEDD8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1-32 from the human protein was used as the immunogen for this NEDD8 antibody.
Limitation:
This NEDD8 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Mouse, Rat, Bovine, Rabbit
Uniprot #:
Q15843