NLRP3 Antibody

NSJ Bioreagents
Product Code: NSJ-F51203
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F51203-0.08ML0.08 ml£260.00
Quantity:
NSJ-F51203-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the NLRP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of NLRP3 antibody and MDA-MB231 lysate~
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NLRP3 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue.

Western blot analysis of NLRP3 antibody and MDA-MB231 lysate~
NLRP3 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue.

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the NLRP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 65-91 from the human protein was used as the immunogen for this NLRP3 antibody.
Limitation:
This NLRP3 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q96P20