PAK5 Antibody

NSJ Bioreagents
Product Code: NSJ-F50894
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F50894-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50894-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the PAK5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC analysis of FFPE human brain tissue stained with PAK5 antibody~
2 / 2
Western blot analysis of PAK5 antibody in lysate from transiently transfected COS7 cells. Lane 1: negative control, and transfected lysates 2: PAK1, 3: PAK2, 4: PAK4,

IHC analysis of FFPE human brain tissue stained with PAK5 antibody~
Western blot analysis of PAK5 antibody in lysate from transiently transfected COS7 cells. Lane 1: negative control, and transfected lysates 2: PAK1, 3: PAK2, 4: PAK4,

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the PAK5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
PAK5 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 168-198 from the human protein was used as the immunogen for this PAK5 antibody.
Limitation:
This PAK5 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
Q9P286