PPP3CC Antibody

NSJ Bioreagents
Product Code: NSJ-F40087
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F40087-0.08ML0.08 ml£260.00
Quantity:
NSJ-F40087-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the PPP3CC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of PPP3CC antibody and HL-60, Jurkat, A375 lysate.~
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IHC analysis of FFPE human breast carcinoma stained with the PPP3CC antibody

Western blot analysis of PPP3CC antibody and HL-60, Jurkat, A375 lysate.~
IHC analysis of FFPE human breast carcinoma stained with the PPP3CC antibody

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the PPP3CC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 18-47 from the human protein was used as the immunogen for this PPP3CC antibody.
Limitation:
This PPP3CC antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P48454