ZAK Antibody (MLKLAK)

NSJ Bioreagents
Product Code: NSJ-F51004
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F51004-0.08ML0.08 ml£260.00
Quantity:
NSJ-F51004-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the ZAK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot analysis of ZAK antibody and HepG2 lysate. There are 3 isoforms of ZAK, visualized at ~91, 51 and 35 kDa.~
2 / 2
IHC analysis of FFPE human hepatocarcinoma tissue stained with the ZAK antibody

Western blot analysis of ZAK antibody and HepG2 lysate. There are 3 isoforms of ZAK, visualized at ~91, 51 and 35 kDa.~
IHC analysis of FFPE human hepatocarcinoma tissue stained with the ZAK antibody

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the ZAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
ZAK/MLKLAK is a member of the MAPKKK family of signal transduction molecules. It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 271-300 from the human protein was used as the immunogen for this ZAK antibody.
Limitation:
This ZAK antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Species Reactivity (Predicted):
Mouse
Uniprot #:
Q9NYL2