c-Abl Antibody

NSJ Bioreagents
Product Code: NSJ-F50696
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F50696-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50696-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the c-Abl antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC analysis of FFPE human hepatocarcinoma tissue stained with c-Abl antibody
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Confocal immunofluorescent analysis of c-Abl antibody with MCF-7 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
3 / 3
Western blot analysis of c-Abl antibody and A2058 lysate. Predicted molecular weight ~120 kDa.

IHC analysis of FFPE human hepatocarcinoma tissue stained with c-Abl antibody
Confocal immunofluorescent analysis of c-Abl antibody with MCF-7 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
Western blot analysis of c-Abl antibody and A2058 lysate. Predicted molecular weight ~120 kDa.

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
Application Note:
Titration of the c-Abl antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 741-769 from the human protein was used as the immunogen for this c-Abl antibody.
Limitation:
This c-Abl antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P00519