MMP7 Antibody

NSJ Bioreagents
Product Code: NSJ-F49501
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F49501-0.08ML0.08 ml£260.00
Quantity:
NSJ-F49501-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the MMP7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Confocal immunofluorescent analysis of MMP7 antibody with 293 cells followed by Alexa Fluor 488-conjugated goat rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
2 / 3
IHC analysis of FFPE human breast carcinoma tissue stained with the MMP7 antibody
3 / 3
Western blot testing of MMP7 antibody and 293 cell lysate

Confocal immunofluorescent analysis of MMP7 antibody with 293 cells followed by Alexa Fluor 488-conjugated goat rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
IHC analysis of FFPE human breast carcinoma tissue stained with the MMP7 antibody
Western blot testing of MMP7 antibody and 293 cell lysate

Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Immunofluorescence: 1:10-1:50
Application Note:
Titration of the MMP7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP7 degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 117-146 from the human protein was used as the immunogen for this MMP7 antibody.
Limitation:
This MMP7 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P09237