RBPJ Antibody

NSJ Bioreagents
Product Code: NSJ-F45603
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F45603-0.08ML0.08 ml£260.00
Quantity:
NSJ-F45603-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot the RBPJ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 3
Western blot testing of RBPJ antibody at 1:2000 dilution and 1) Ramos, 2) human pancreas lysate; Predicted molecular weight ~ 56 kDa.
2 / 3
Fluorescent confocal image of A2058 cell stained with RBPJ antibody. Alexa Fluor 488 conjugated secondary (green) was used. RBPJ immunoreactivity is localized to the nucleus.
3 / 3
RBPJ antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue.

Western blot testing of RBPJ antibody at 1:2000 dilution and 1) Ramos, 2) human pancreas lysate; Predicted molecular weight ~ 56 kDa.
Fluorescent confocal image of A2058 cell stained with RBPJ antibody. Alexa Fluor 488 conjugated secondary (green) was used. RBPJ immunoreactivity is localized to the nucleus.
RBPJ antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue.

Further Information

Application Details :
Western blot: 1:1000-2000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
Application Note:
Titration of the RBPJ antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1-29 from the human protein was used as the immunogen for this RBPJ antibody.
Limitation:
This RBPJ antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
Q06330